Endocrine Abstracts

The aim of the study was to investigate insulin resistance, dyslipidemia and atherogenic factors influencing HDL functions in symple obesity (SO) and obesity with acanthosis nigricans (OAN). Althogether 37 children with obesity, 17 girls and 20 boys, 19 with SO and 18 with OAN, were included into the study. Their age was 14.2±1.8 years and BMI was 35.9±6.1 kg/m2.Fasting glucose (FG), insulin (INS) were measured and HOMA-IR was calcul...

Aim: Chemerin, a recently discovered adipokine produced by the adipose tissue and liver, along with other atherosclerosis markers, was associated lately with metabolic syndrome and acts as chemoattractant for immune cells may also regulate immune cell properties. Autoimmune Hashimoto’s thyroiditis even with sTSH levels corrected to be within the normal range values may be accompanied by dyslipidemia presenting increased total-C, TG, LDL-C, and Lp(a), all of which are pote...

Adipose tissue secreted hormonal mediators, adipokines play pivotal roles in the regulation of, among others, central nervous and immune systems influencing body weight, insulin action and inflammatory responses. The aim of our present study was to investigate possible associations of thyroid function with plasma levels of three of known adipokines, i.e. leptin, adiponectin and resistin in 74 Caucasian subjects without any endocrine diseases or related therapy. In order to cre...